Missouri’s attorney general is urging lawmakers to pass legislation cracking down on the fentanyl crisis.

The smoke has affected parts of the Midwest and could affect other areas soon.

Fire crews are investigating smoke at the Jamestown Mall in north St. Louis County Tuesday around 7:30 a.m.

Missouri Gov. Mike Parson on Monday declined clemency for a man who faces execution Tuesday evening for killing two jailers in an ill-fated effort to free someone else from a county jail.

As the St. Louis region continues to battle drought conditions, lawns, plants and flowers are struggling to beat the early summer heat.

The O’Fallon Police Department is trying to identify an Amazon delivery driver who was caught on video picking up a dropped wallet.

An O’Fallon, Missouri man has been charged after police say he fired at least two shots into a car on MO 364 in St. Charles County on May 26.

Attention on the crash and its cause was heightened by its unusual flight path over Washington and a sonic boom caused by military aircraft heard across D.C. and parts of Maryland and Virginia.

President Joe Biden says the Kansas City Chiefs are “building a dynasty” as he hosts the team at the White House to mark their Super Bowl victory in February

An attorney for a man on Missouri's death row says her client is on “an emotional roller coaster” amid efforts to spare his life with just a day to go before his scheduled execution

St. Louis Cardinals right-hander Leonardo Taveras was suspended for 80 games under baseball’s minor league drug program following a positive test for the performance-enhancing substance Clomiphene

The St. Louis Metropolitan Police Department wants the community to step up to crack the cold case.